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Old 03-20-2010, 03:11 PM   #1
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Default Microvascular Dysplasia

My 15 month sweet little boy has had bile acids over 1300 and just had a cat scan and biopsy done to determine if there was a shunt present. Luckily there is no shunt, but the biopsy results came in and he does have microvascular dysplasia. He is currently on metronitonzale and lactolose and eats a perscription K/D diet. What should I do to help him, would different food or medicine be helpful. I have talked with others with yorkies with microvascular dysplasia who have bile acid counts between 75-100. My Timmys is so much higher and I am worried. If anyone could help me with information, I would GREATLY appreciate it!
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Old 03-20-2010, 03:21 PM   #2
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Originally Posted by Rklane56 View Post
My 15 month sweet little boy has had bile acids over 1300 and just had a cat scan and biopsy done to determine if there was a shunt present. Luckily there is no shunt, but the biopsy results came in and he does have microvascular dysplasia. He is currently on metronitonzale and lactolose and eats a perscription K/D diet. What should I do to help him, would different food or medicine be helpful. I have talked with others with yorkies with microvascular dysplasia who have bile acid counts between 75-100. My Timmys is so much higher and I am worried. If anyone could help me with information, I would GREATLY appreciate it!
I'm sorry...that has to be breaking your heart. I have no experience but there are some here who will be able to offer advice - also you can search the site and read more information while you wait for people to see this.

All the best to you !
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Old 03-20-2010, 04:23 PM   #3
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Originally Posted by Rklane56 View Post
My 15 month sweet little boy has had bile acids over 1300 and just had a cat scan and biopsy done to determine if there was a shunt present. Luckily there is no shunt, but the biopsy results came in and he does have microvascular dysplasia. He is currently on metronitonzale and lactolose and eats a perscription K/D diet. What should I do to help him, would different food or medicine be helpful. I have talked with others with yorkies with microvascular dysplasia who have bile acid counts between 75-100. My Timmys is so much higher and I am worried.f anyone could help me with information, I would GREATLY appreciate it!
Buster's BAT was 155, not nearly as high as your Timmy's. He is not on any medication but he does eat Purina EN. He did not have a biopsy only the ultra sound which I have heard can't determine if there is a shunt. The vet at Texas A&M Vet Clinic made the diagnosis of no shunt which was good to hear. He seems to be doing ok. He eats a bit more than he did but he has not vomited in a while. I would keep doing what the vet has recommended as I'm not sure if there is much else that can be done. It's tough wondering if there is anything else you can do for them.
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Old 03-20-2010, 04:27 PM   #4
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There's a Yahoo group you can join where they have a lot of information and a protocol for LS and MVD dogs. Are you a member of that group?

My Lucy has MVD too - but so far very mild with no symptoms. Her last test was 35 so much less than the numbers you have.

1300 sounds like a lot. Is your dog having any symptoms . . .or doing well on the protocol you have him on now?
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Old 03-20-2010, 05:50 PM   #5
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That does seem high for MVD. My Cali has a very mild case, diagnosed by Bile acid tests and confirmed with a liver biopsy. Her BA were below 100. Are they going to redo his bile acid test after a few months on medicine and diet?
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Old 03-21-2010, 09:12 AM   #6
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I'm sorry to hear your baby has MVD. Our dog Daisy was diagnosed with MVD at age 6 -- our vet just did not know what was wrong with her all those years so you are lucky to find out early in your baby's life. Our Daisy went on the Hill's L/D diet initially, along with milk thistle (we use the product Marin). She is now on a home cooked diet formulated just for her as her situation is complicated by severe allergies and IBD.

Daisy does great and is well managed medically. Lots of dogs with MVD do great on the right diet.

I just wanted to also tell you that Daisy's BAT and overall liver functioning have IMPROVED consistently since her diagnosis. So it is possible!

I wish you good luck!
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Old 03-21-2010, 12:39 PM   #7
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1300? Are you sure that isn't one of the liver enzymes?

If it's MVD, K/D is not recommended. L/D canned is preferred or Royal Canin LS 14 Hepatic kibble.

SAMe (Denosyl or some use Vetri DMG) should be given.
Milk thistle is also good (Hepato Support seems to be the favorite for severely liver compromised dogs). Some give vitamin e also.

Any symptoms?
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Old 03-21-2010, 04:34 PM   #8
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The only symptoms he has currently is he shakes once in a while. the bile acids were 1300 which I thought was insane. He is doing ok on the K/D, he is on that because of the low protein. The medicine so far he is ok on...The biopsy said to be MVD, but I have never heard of anyones yorkie having bile acids over 100!
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Old 03-21-2010, 04:36 PM   #9
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That does seem high for MVD. My Cali has a very mild case, diagnosed by Bile acid tests and confirmed with a liver biopsy. Her BA were below 100. Are they going to redo his bile acid test after a few months on medicine and diet?
They have done several bile acid tests since september, he has been on the medicine since then and no change. The vet told me there would be no decrease!
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Old 03-21-2010, 04:38 PM   #10
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Buster's BAT was 155, not nearly as high as your Timmy's. He is not on any medication but he does eat Purina EN. He did not have a biopsy only the ultra sound which I have heard can't determine if there is a shunt. The vet at Texas A&M Vet Clinic made the diagnosis of no shunt which was good to hear. He seems to be doing ok. He eats a bit more than he did but he has not vomited in a while. I would keep doing what the vet has recommended as I'm not sure if there is much else that can be done. It's tough wondering if there is anything else you can do for them.

Purina EN is VERY high in protein! I have a poodle on that because she has inflamatory bowel disease. Is your yorkie doing ok on the EN. I wish I knew what I could do, I feel helpless not being able to help him!
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Old 03-21-2010, 04:41 PM   #11
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Are you going to an internist?

I believe Actigall can bring the bile acids down, but they would no longer be measurable.

The K/D is not recommended because there is pork in it which is hard on the liver. Vets tend to use it because they see the low protein and think it's a great choice, but low protein isn't all that is needed. They tpe of protein given is very important. Some types cause toxins to build up faster and that causes symptoms. SAMe is generally considered a very important part of liver shunt and MVD in severe cases...
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Old 03-21-2010, 05:32 PM   #12
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Are you going to an internist?

I believe Actigall can bring the bile acids down, but they would no longer be measurable.

The K/D is not recommended because there is pork in it which is hard on the liver. Vets tend to use it because they see the low protein and think it's a great choice, but low protein isn't all that is needed. They tpe of protein given is very important. Some types cause toxins to build up faster and that causes symptoms. SAMe is generally considered a very important part of liver shunt and MVD in severe cases...

I have an appointment with an internist april 1st!...I will switch him right away to L/D... What is SAMe?
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Old 03-21-2010, 07:50 PM   #13
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1300? Are you sure that isn't one of the liver enzymes?

If it's MVD, K/D is not recommended. L/D canned is preferred or Royal Canin LS 14 Hepatic kibble.

SAMe (Denosyl or some use Vetri DMG) should be given.
Milk thistle is also good (Hepato Support seems to be the favorite for severely liver compromised dogs). Some give vitamin e also.

Any symptoms?
yeah 1300 does not sound right and have never heard of a cat scan being done for this it is usually a scintigraphy to determine a liver shunt so i am really confused - is your dog having symptoms?

ask vet what pre and post bile acid numbers are and ask vet what ALT is and what is normal for that lab
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Old 03-22-2010, 04:13 AM   #14
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yeah 1300 does not sound right and have never heard of a cat scan being done for this it is usually a scintigraphy to determine a liver shunt so i am really confused - is your dog having symptoms?

ask vet what pre and post bile acid numbers are and ask vet what ALT is and what is normal for that lab

His ALT levels are normal, they are 25...They said that they put a dye into his system to see the flow of his blood to see if it is shunting, which is what I thought a scintigraphy was, but they called it a cat scan. He acted almost drunk (standing still and wobbling, rocking back and forth) the day we started this, but now on the mediucine he shakes once in a while. I don't know if he has some hypergylcimea or if that is something associated with MVD.
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Old 03-22-2010, 01:25 PM   #15
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I just found out that his bile acids were 129, and it was his liver enzymes that were 1329. But his ALT level was 25, normal!
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